For adults who are taking other high blood pressure medicines and whose blood pressure is not well controlled

Help lower difficult-to-control hypertension by adding once-daily TRYVIO.

Ask your doctor about TRYVIO today.

LEARN HOW TO GET PRESCRIPTION SAVINGS

If you’ve been struggling to lower your high blood pressure, TRYVIO may be able to help.

High blood pressure causes increased cardiovascular (CV) risk, so even small blood pressure reductions can help. Studies have shown that lowering high blood pressure reduces the risk of heart attacks and strokes.

Highlights of TRYVIO

1 tablet, taken once a day

Helps reduce high blood pressure

Can be taken with other medications

TRYVIO360 helps you start and stay on track with TRYVIO

How to get TRYVIO

TRYVIO is only available through Walgreens Specialty Pharmacy. Here’s what to expect as you get started:

STEP 1:

Your doctor will send your TRYVIO prescription to Walgreens Specialty Pharmacy.

STEP 2:

Walgreens Specialty Pharmacy will contact you to discuss insurance coverage and collect shipping information.

STEP 3:

Within a few days, Walgreens Specialty Pharmacy will ship TRYVIO to your home or preferred location.

TRYVIO Patient Support

Ask your doctor about a 30-day free trial offer for your first TRYVIO prescription, regardless of your insurance.a

Commercially eligible patients may also receive TRYVIO for as little as $10 per month.b

TRYVIO Copay card

aLimitations apply. This offer is good for a 30-day (maximum 30 tablets; one time use) free trial of TRYVIO at no cost to you. See full Terms and Conditions.

bLimitations apply. For commercially eligible patients only. This offer is not valid under Medicare, Medicaid, or any other federal or state program. Patient must be 18 years of age or older and a resident of the United States. See full Terms and Conditions.

Ask your doctor how TRYVIO may be able to help lower your blood pressure.

IMPORTANT SAFETY INFORMATION AND INDICATION

What is the most important information I should know about TRYVIO?

TRYVIO may cause serious side effects, including:

Serious birth defects.

  • TRYVIO may cause serious birth defects if taken during pregnancy.
  • Females who can become pregnant should not be pregnant when they start taking TRYVIO or become pregnant during treatment with TRYVIO or for 1 month after stopping treatment with TRYVIO.
  • Females who can become pregnant should have a negative pregnancy test before starting treatment with TRYVIO.
    • Females who can become pregnant are females who:
      • have entered puberty, even if they have not started their menstrual period, and
      • have a uterus, and
      • have not gone through menopause. Menopause means that you have nothad a menstrual period for at least 12 months for natural reasons, or that you have had your ovaries removed.
    • Females who cannot become pregnant are females who:
      • have not yet entered puberty, or
      • do not have a uterus, or
      • have gone through menopause. Menopause means that you have not had a menstrual period for at least 12 months for natural reasons, or that you have had your ovaries removed, or
      • are infertile for other medical reasons and this infertility is permanent and cannot be reversed.
  • Females who can become pregnant should use effective birth control during treatment with TRYVIO, and for 1 month after stopping TRYVIO because the medicine may still be in your body.
    • Talk with your healthcare provider or gynecologist (a healthcare provider who specializes in female reproduction) to find out about options for effective birth control that you may use to prevent pregnancy during treatment with TRYVIO.
    • If you decide that you want to change the form of birth control that you use, talk with your healthcare provider or gynecologist to be sure that you choose another acceptable form of birth control.
  • Do not have unprotected sex. Talk to your healthcare provider or pharmacist right away if you have
    unprotected sex or if you think your birth control has failed. Your healthcare provider may talk with you
    about using emergency birth control.
  • Tell your healthcare provider right away if you miss a menstrual period or you think you might be
    pregnant.

Who should not take TRYVIO?

Do not take TRYVIO if you are:

  • Pregnant or currently trying to become pregnant.
  • allergic to aprocitentan or any of the ingredients in TRYVIO.

Before taking TRYVIO, tell your healthcare provider about all of your medical conditions, including if you:

  • have liver problems
  • have heart failure
  • have anemia
  • have kidney problems or get dialysis
  • are pregnant or plan to become pregnant during treatment with TRYVIO. TRYVIO can cause serious birth defects.
  • are breastfeeding or plan to breastfeed. It is not known if TRYVIO passes into your breastmilk. Do not breastfeed if you take TRYVIO. Talk to your healthcare provider about the best way to feed your baby if you take TRYVIO.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter
medicines, vitamins, and herbal supplements.

What are the possible side effects of TRYVIO? TRYVIO may cause serious side effects, including:

  • Serious birth defects.
  • Liver problems. TRYVIO may cause liver problems. Your healthcare provider should do blood tests to check your liver before starting treatment and as needed during treatment with TRYVIO. Tell your healthcare provider if you have any of the following symptoms of liver problems during treatment with TRYVIO:
    • nausea or vomiting
    • yellowing of your skin or whites of your eyes
    • pain in the upper right stomach
    • dark urine
    • tiredness
    • fever
    • loss of appetite
    • itching
  • Fluid retention. Fluid retention and swelling are common during treatment with TRYVIO and can be
    serious. Tell your healthcare provider right away if you have any unusual weight gain, trouble breathing,
    or swelling of your ankles or legs. Your healthcare provider may treat you with other medicines
    (diuretics) if you develop fluid retention or swelling.
  • Low red blood cell levels (anemia). Anemia is common during treatment with TRYVIO and can be
    serious. Your healthcare provider will do blood tests to check your red blood cells before starting and as
    needed during treatment with TRYVIO.
  • Decreased sperm count. TRYVIO may cause decreased sperm counts in males and may affect the
    ability to father a child. Tell your healthcare provider if being able to have children is important to you.

Your healthcare provider may stop treatment with TRYVIO if you develop certain side effects. Tell your
healthcare provider if you have any side effect that bothers you or that does not go away.  These are not all the possible side effects of TRYVIO. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Please read the Medication Guide for TRYVIO and discuss it with your healthcare provider.

What is TRYVIO?

TRYVIO is a prescription medicine used to treat high blood pressure (hypertension) in adults who are taking other high blood pressure medicines and whose blood pressure is not well controlled. It is not known if TRYVIO is safe and effective in children.

To top

IMPORTANT SAFETY INFORMATION AND INDICATION

What is the most important information I should know about TRYVIO?

TRYVIO may cause serious side effects, including:

Serious birth defects.

  • TRYVIO may cause serious birth defects if taken during pregnancy.
  • Females who can become pregnant should not be pregnant when they start taking TRYVIO or become pregnant during treatment with TRYVIO or for 1 month after stopping treatment with TRYVIO.
  • Females who can become pregnant should have a negative pregnancy test before starting treatment with TRYVIO.
    • Females who can become pregnant are females who:
      • have entered puberty, even if they have not started their menstrual period, and
      • have a uterus, and
      • have not gone through menopause. Menopause means that you have nothad a menstrual period for at least 12 months for natural reasons, or that you have had your ovaries removed.
    • Females who cannot become pregnant are females who:
      • have not yet entered puberty, or
      • do not have a uterus, or
      • have gone through menopause. Menopause means that you have not had a menstrual period for at least 12 months for natural reasons, or that you have had your ovaries removed, or
      • are infertile for other medical reasons and this infertility is permanent and cannot be reversed.
  • Females who can become pregnant should use effective birth control during treatment with TRYVIO, and for 1 month after stopping TRYVIO because the medicine may still be in your body.
    • Talk with your healthcare provider or gynecologist (a healthcare provider who specializes in female reproduction) to find out about options for effective birth control that you may use to prevent pregnancy during treatment with TRYVIO.
    • If you decide that you want to change the form of birth control that you use, talk with your healthcare provider or gynecologist to be sure that you choose another acceptable form of birth control.
  • Do not have unprotected sex. Talk to your healthcare provider or pharmacist right away if you have
    unprotected sex or if you think your birth control has failed. Your healthcare provider may talk with you
    about using emergency birth control.
  • Tell your healthcare provider right away if you miss a menstrual period or you think you might be
    pregnant.

Who should not take TRYVIO?

Do not take TRYVIO if you are:

  • Pregnant or currently trying to become pregnant.
  • allergic to aprocitentan or any of the ingredients in TRYVIO.

Before taking TRYVIO, tell your healthcare provider about all of your medical conditions, including if you:

  • have liver problems
  • have heart failure
  • have anemia
  • have kidney problems or get dialysis
  • are pregnant or plan to become pregnant during treatment with TRYVIO. TRYVIO can cause serious birth defects.
  • are breastfeeding or plan to breastfeed. It is not known if TRYVIO passes into your breastmilk. Do not breastfeed if you take TRYVIO. Talk to your healthcare provider about the best way to feed your baby if you take TRYVIO.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter
medicines, vitamins, and herbal supplements.

What are the possible side effects of TRYVIO? TRYVIO may cause serious side effects, including:

  • Serious birth defects.
  • Liver problems. TRYVIO may cause liver problems. Your healthcare provider should do blood tests to check your liver before starting treatment and as needed during treatment with TRYVIO. Tell your healthcare provider if you have any of the following symptoms of liver problems during treatment with TRYVIO:
    • nausea or vomiting
    • yellowing of your skin or whites of your eyes
    • pain in the upper right stomach
    • dark urine
    • tiredness
    • fever
    • loss of appetite
    • itching
  • Fluid retention. Fluid retention and swelling are common during treatment with TRYVIO and can be
    serious. Tell your healthcare provider right away if you have any unusual weight gain, trouble breathing,
    or swelling of your ankles or legs. Your healthcare provider may treat you with other medicines
    (diuretics) if you develop fluid retention or swelling.
  • Low red blood cell levels (anemia). Anemia is common during treatment with TRYVIO and can be
    serious. Your healthcare provider will do blood tests to check your red blood cells before starting and as
    needed during treatment with TRYVIO.
  • Decreased sperm count. TRYVIO may cause decreased sperm counts in males and may affect the
    ability to father a child. Tell your healthcare provider if being able to have children is important to you.

Your healthcare provider may stop treatment with TRYVIO if you develop certain side effects. Tell your
healthcare provider if you have any side effect that bothers you or that does not go away.  These are not all the possible side effects of TRYVIO. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Please read the Medication Guide for TRYVIO and discuss it with your healthcare provider.

What is TRYVIO?

TRYVIO is a prescription medicine used to treat high blood pressure (hypertension) in adults who are taking other high blood pressure medicines and whose blood pressure is not well controlled. It is not known if TRYVIO is safe and effective in children.